I would guess that potential "clotting" or "clogging" would show up as a precipitate as opposed to easy dispersion of one liquid into the other. Might be very difficult to see in the darker colors. If you were to dilute the darker color samples, either before or after mixing them, I don't know if you would either prevent or disolve the precipitate and mask a negative result. Although the relative Ph of one to the other would be the same after dilution, the actual Ph would be altered. That may not be the only issue that would cause compatability issues, but it would be a major issue if one were acidic and one basic.